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Medical Xpress is a web-based medical and health news service that is part of the renowned Science X network. Based on the years of experience as a Phys.org medical research channel, started in April 2011, Medical Xpress became a separate website.
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The News summary below is based on the query - "Adipose + Derived + Cells"
 

Medical Xpress - latest medical and health news stories

21 April 2019

Medical Xpress internet news portal provides the latest news on Health and Medicine.
  • A step toward recovering reproduction in girls who survive childhood cancer
    Leukemia treatments often leave girls infertile, but a procedure developed by researchers at the University of Michigan working with mice is a step toward restoring their ability to be biological mothers.
  • New therapeutic avenue in the fight against chronic liver disease
    An international team of researchers has identified a novel route that regulates the signaling pathways induced by extracellular matrix (ECM). This may serve as a new diagnostic marker and therapeutic target in the fight against chronic liver diseases.
  • Platelets grown from stem cells may be alternative to donated platelets
    Researchers have developed a way to grow human platelets in the laboratory from stem cells derived from fat tissue. The achievement, reported today in the journal Blood, suggests manufactured platelets could eventually reduce the reliance on donated platelets to help patients with cancer and other disorders.
  • 3-D bioPen: A hydrogel injection to regenerate cartilage
    Highly specialized cartilage is characteristically avascular and non-neural in composition with low cell numbers in an aliphatic environment. Despite its apparent simplicity, bioengineering regenerative hyaline cartilage in a form effective for implantation remains challenging in musculoskeletal tissue engineering. Existing surgical techniques including autologous chondrocyte implantation (ACI) and matrix-induced autologous chondrocyte implantation (MACI) are considered superior to self-repair induction techniques. However, both MACI and ACI are complex, multistage procedures that require a double operation; first for surgical excision of native cartilage, followed by expansion of adult chondrocytes in vitro prior to implantation by a second operation.
  • Obesity study reports the heritability of adipose tissue composition
    A multi-institutional team of researchers led by Jan-Wilhelm Kornfeld, Elena Schmidt and Martin Bilban has made a groundbreaking discovery in obesity research.
  • Healthy fat cells uncouple obesity from diabetes
    About 422 million people around the world, including more than 30 million Americans, have diabetes. Approximately ninety percent of them have type 2 diabetes. People with this condition cannot effectively use insulin, a hormone made by the pancreas that helps the body turn blood sugar (glucose) into energy.
  • Platelet-rich plasma does not promote stem cell-mediated cartilage repair
    Platelet-rich plasma (PRP) is believed to provide pain relief and help improve joint function in degenerative joint disease, but a new study has shown that it does not act by promoting stem cell proliferation or enhance the cartilage formation capabilities of mesenchymal stem cells (MSCs). The effects of PRP treatment on cartilage formation and chondrogenesis in the presence of adult human MSCs derived from two different sources are reported in the study published in Tissue Engineering, Part A.
  • Researchers discover gene that controls bone-to-fat ratio in bone marrow
    In an unexpected discovery, UCLA researchers have found that a gene previously known to control human metabolism also controls the equilibrium of bone and fat in bone marrow as well as how an adult stem cell expresses its final cell type. The findings could lead to a better understanding of the disruption of bone-to-fat ratio in bone marrow as well as its health consequences, and also point to the gene as a promising therapeutic target in the treatment of osteoporosis and skeletal aging.
  • Removing barriers to healing
    Severe inflammation caused by a patient's immune system can be deadly, but stem cells found in human fat could provide new ways to protect against this toxic reaction.
  • Culprit in reducing effectiveness of insulin identified
    Scientists at Osaka University have discovered that Stromal derived factor-1 (SDF-1) secreted from adipocytes reduces the effectiveness of insulin in adipocytes and decreased insulin-induced glucose uptake.

 

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