No, it does not require heat activation beyond vortexing for the encapsulation. To complete the pharmaceutical dosage form preparation the final step is freeze and dry (lyophilization). The final product should be fluffy for sterile water/saline reconstitution.
All components (in solution forms) for the liposomal compounding should all be considered commonly acceptable materials to pass the FDA requirements.
The diameters of most liposomal preparations would not allow living cells encapsulation. I think Hedrick is working on encapsulation of certain cellular components/substracts (second generation regenerative medicine). I believe Histogen /Gail Naughton has the same idea. (I believe that I have met Gail Naughton before and she is very impressive.)
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