Welcome, Guest
Username: Password: Remember me
Household affairs and private business
  • Page:
  • 1

TOPIC: Today-Nov 2-is Vitamin D Day

Today-Nov 2-is Vitamin D Day 02 Nov 2015 06:22 #5384

  • fas
  • fas's Avatar Topic Author
  • Offline
  • Moderator
  • Moderator
  • May the fat be with you
  • Posts: 3291
  • Thank you received: 1110


Link to the website celebrating this day: Vitamindday.net

As my personal contribution to this day, I would like to share the latest news from the Linus Pauling Institute in Oregon.

As you probably know- the late Linus Pauling is one of the few people in the history of mankind, who received two Nobel Prizes- another one that comes to mind is Madame Curie.

As somebody who prefers to eliminate pharmacological side effects, which are often more dangerous than the disorder they are trying to cure, I am visiting their page quite often to stay up-to-date of developments in the natural health field.

Link to article : Linus Pauling Institute Article

October 22, 2015

CORVALLIS, Ore. – A growing body of evidence suggests that two natural compounds, vitamin D and xanthohumol, have the ability to address imbalances in gut microbiota that may set the stage for obesity and metabolic syndrome - problems that affect about one out of every three adults in the United States.

To explore and identify the specific mechanisms by which these compounds have beneficial effects, researchers in the Linus Pauling Institute at Oregon State University have received a new five-year, $2.64 million grant from the National Institutes of Health.

The possible payoff of this research, they say, may be an entirely new way to reduce or prevent some of the major diseases that are killing millions of people every year, such as heart disease and type-2 diabetes.

The new approach would attempt, using high dose supplementation, to prevent disease from developing, instead of treating it after the fact.

“The benefits of xanthohumol and vitamin D have been clearly shown in laboratory studies to reduce weight gain and improve gut barrier defenses,” said Adrian Gombart, an associate professor of biochemistry and biophysics in the OSU College of Science, and a principal investigator with the Linus Pauling Institute. “These compounds appear to activate nuclear receptors and pathways that may affect microbe composition, and in the process reduce the damage from metabolic syndrome.”

One study published by OSU researchers two years ago in the Journal of Biological Chemistry found that rats given xanthohumol supplements, which are made from hops, had a 14 percent reduction in weight gain, a 25 percent reduction in plasma fasting glucose, and improved lipid metabolism, compared to a control group of rats that ate the same amount of food. They had a higher rate of fatty acid oxidation and energy metabolism. In simple terms, they burned more fat.

In other studies, higher levels of vitamin D status in humans have been associated with reduced risk of obesity, metabolic syndrome, cancer, infectious diseases, autoimmune diseases, and other health problems.

Other lead investigators on this research include Claudia Maier, an OSU professor of chemistry; Fred Stevens, a professor in the OSU College of Pharmacy and also a principal investigator with the Linus Pauling Institute; and Balz Frei, a distinguished professor of biochemistry and biophysics, and director of the Linus Pauling Institute.

The OSU researchers believe some of the benefits of vitamin D and/or xanthohumol may be a strong increase in the expression of the cathelicidin antimicrobial peptide, or CAMP gene. The hypothesis to be tested in this research, using animal models, is that higher CAMP levels improve gut epithelial barrier function, reduce inflammation, modify gut microbiota and in the process reduce problems with obesity and metabolic syndrome.

“Some of the benefits we’re seeing are fairly clear and dramatic, and we need to better understand the mechanisms that cause them,” Stevens said.

The compounds may also affect liver function, shutting down metabolic pathways that produce fat and glucose, he said.

Vitamin D can be obtained through either the diet or produced by the skin, with adequate exposure to sunshine. Millions of people who live in temperate zones around the world, however, have been found to have inadequate levels of this vitamin, but this can be corrected by taking a supplement.

Xanthohumol, a flavonoid, is also a natural compound and is found in the hops used to make beer. Researchers point out, however, that the levels of xanthohumol being used in this research greatly exceed any amount that could be obtained by drinking beer.

Direct health care costs arising from obesity and related disorders accounts for almost 10 percent of U.S. health care expenditures each year, the researchers said. The health care costs of diabetes alone were estimated in the U.S. at $176 billion in 2012, and it’s one of the leading causes of death in the nation.


A few Million from the NIH is good enough for me to to try out natural hops- the beer ingredient!- I already have a sufficient intake of Vit D.. :yep:



Picture : Hops growing

Please Log in or Create an account to join the conversation.

Board moderator and Site-owner. I still regret the day I started analysing the prospects of MacroPore (now Cytori) back in 2004- a left-over from the tech-bubble at that time from the century change in my portfolio- and became addicted to Cytori´s fat cell technology. :cry:

Today-Nov 2-is Vitamin D Day 02 Nov 2015 10:11 #5388

  • fatboy
  • fatboy's Avatar
  • Offline
  • Platinum Boarder
  • Platinum Boarder
  • Posts: 416
  • Thank you received: 77
Fas,

How much vitamin d do you take? And in what form?

Please Log in or Create an account to join the conversation.

Today-Nov 2-is Vitamin D Day 02 Nov 2015 12:05 #5389

  • fas
  • fas's Avatar Topic Author
  • Offline
  • Moderator
  • Moderator
  • May the fat be with you
  • Posts: 3291
  • Thank you received: 1110

How much vitamin d do you take? And in what form?


Fatboy- I think I get 99% of my vitamin D3 from supplements- in my case Healthy Origins 10.000 IU capsules of which I take one on a daily basis.

In the past I did spend quite some time in the sun- the other way of taking in D3- that is over the skin, but in April this year, after having major issues with being totally tired and without energy, I had my level measured and came out at 6 ng/ml- absolutely deficient.

Next step was put this value in a measurement program, which spits out - given your weight and starting level and where you want to go- what you should take.
That brought me to 66 ng/ml- measured in serum and my target was 65- so the program worked well for me. Taking 10.000 IU should keep me between 80-90, which is what I want to have protection against cancer and cardiac issues. That is all well proven- in the spring next year, I will check again.



Anyway- a good level brings health and whats also important- a good mood. :grin:

And you have to live in Florida really to get enough sun on your skin for sufficient D3 levels. Mercola walks an hour over the beach everyday, with only a cap and swimming trunks.. :whistle:

Please Log in or Create an account to join the conversation.

Board moderator and Site-owner. I still regret the day I started analysing the prospects of MacroPore (now Cytori) back in 2004- a left-over from the tech-bubble at that time from the century change in my portfolio- and became addicted to Cytori´s fat cell technology. :cry:

Today-Nov 2-is Vitamin D Day 03 Nov 2015 07:10 #5390

  • fas
  • fas's Avatar Topic Author
  • Offline
  • Moderator
  • Moderator
  • May the fat be with you
  • Posts: 3291
  • Thank you received: 1110
Just for the record...

The image in the prior post shows deficiency below 50 ng/ml. That is the opinion of experts on the subject, which are different than recommendations of National Health Agencies. Both in the US and Europe a level below 20 ng/ml I believe they regard as deficient. :whistle:

Just like so many things which would "hurt" Big Pharma, this is another example of almost criminal behaviour against the population of those countries and definitely bad nutrition advice.

Anyway- for those who have an interest in the subject- view this condensed video of Mercola with Dr. Michael Holick, who has been researching Vitamin D3 for over 40 years and was the discoverer of the bioactive component. You can also see him as the "D3 Pope". :grin:



I also attach the transcript of the long versions of the interview, which you can browse through. One of the last statements/comments I found most impressive...

MH: Well, just one other: we did a study recently, because we asked a simple question; how does your body really know your vitamin D status? Ultimately, it’s probably your genes that know. We did a study in healthy adults. We gave them 2,000 units of vitamin D a day for a few months. We got the white blood cells and looked at broad-gene expression of over 22,500 genes.
Long story short…
JM: Is that the entire genome?
MH: Yes, that’s correct. Yup. So, we’ve got the white blood cells at the beginning and at the end of the study. We identified 291 genes that were influenced just by increasing your vitamin D intake. These genes control up to 80 different metabolic processes, from improving DNA repair to having effect on autoxidation (which is, of course, a big deal for aging, cancer, and the like), also for your immune system, as well as for a lot of other processes.


File Attachment:

File Name: Interview-DrHolick.pdf
File Size: 241 KB
Attachments:

Please Log in or Create an account to join the conversation.

Board moderator and Site-owner. I still regret the day I started analysing the prospects of MacroPore (now Cytori) back in 2004- a left-over from the tech-bubble at that time from the century change in my portfolio- and became addicted to Cytori´s fat cell technology. :cry:
  • Page:
  • 1
Time to create page: 0.109 seconds

Copyright Information

Copyright Fas Kuiters © 2016 young-foxes.com. All Rights Reserved.
This page is made with Joomla CMS and its various templates designed by Fas Kuiters with the excellent Themler tool.

 

 

Shared Spreadsheet Links

DOV´s Revised Projections for the Periods 2017 until 2020

Shareble link : HERE

Fas Kuiters Websites